Research Projects & Promotion

Standardization of quantitative cccDNA measurements

ICE-HBV participates to the DZIF-ANRS international research project on the standardization of quantitative cccDNA measurements.

The objective of this project is to develop reliable laboratory protocols for cccDNA quantification by  comparing  head  to  head  different  methodologies  and  by  exploring  new  strategies  to  improve  specificity of cccDNA qPCRs. Because of the need of international expertise and cross‐validation  among laboratories, different research groups worldwide (both academic and from industry) are currently involved.

in-vivo Models

Better in-vivo models are required to study HBV cures. ICE-HBV held an workshop on this topic in October 2019, which led to the publication of a review article.

Serum Biomarkers

ICE-HBV held online workshop on serum biomarkers of HBV, on 4 October 2020, to build consensus in this area and accelerate cure research. A consensus statement on the topic will be published in 2021.

The Management of CHB in Ressource-Limited Settings

ICE-HBV is addressing the challenge of managing HBV in contexts where access to technology is limited. A global project group of experts is preparing recommendations on the topic.

Community Scientific Literacy Workshops & Webinars

ICE-HBV informs the community about HBV research, making science accessible to all, with a focus on informing people affected by hepatitis B, for instance at the NoHep Village in Toronto in June 2018. 

ICE-HBV and The Hepatitis B Foundation also hold a yearly webinar on HBV cure for the community. You can watch the 2020 edition here.

Health Policy

ICE-HBV stakeholders collaborate to ensure appropriate HBV cure preparedness.

They come together to organize health policy activities at major events such as the Global Fund replenishment conference. 

The Potential Impact of a Cure for Chronic Hepatitis B Infection: A Population Health and Economic Analysis in Australia, China and the USA

ICE-HBV sparked a collaboration between Stanford Medical School, University of Michigan and the Doherty Institute on HBV Cure modelling. You can find the first presentation from Dr Toy here.

Events & Research Promotion Activities

ICE-HBV participates, promotes and partners with existing HBV cure events worldwide. Partnerships currently exist with the International HBV Meeting, the Science of HBV Cure, the ANRS Workshop on HBV Cure.