The ultimate aim of HBV cure regimens should be the eradication of the virus. However, functional cure may be a more realistic goal. A combination of strategies which target the viral replication cycle and enhance the immune response will most likely be required. More.
The World Health Organization has stated that viral hepatitis is an international public health challenge comparable to other major communicable diseases, including HIV, tuberculosis and malaria. Chronic HBV infection results in 887,000 death per year from cirrhosis and liver cancer. More.
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