9th HBV Cure Workshop supported by ANRS | Emerging Infectious Diseases

The 9th HBV Cure Workshop, organized by ANRS | EID, will take place on Tuesday, July 5, 2022. This year, the meeting will be organized in Lyon, France and online.

Learn more about the event here

Program

9:30 am – 9:45 am Welcome 

Yazdan Yazdanpanah (Director of ANRS) & Fabien Zoulim (ANRS HBV cure Task Force)

9:45 am – 11:15 am Session I: Clinical trials

Chairs: Hélène Fontaine & Jean-Michel Pawlotsky  

•  Clinical development of direct acting antivirals for chronic hepatitis B – MF Yuen (Hong Kong) 
• Clinical development of immune therapies for chronic hepatitis B –Harry Janssen (Rotterdam, the Netherlands) 
• Emerging therapies for chronic hepatitis Delta –Marc Bourlière (Marseille, France) 

Roundtable discussion: what will be the best combination strategies ? 

11:15 am – 11:30 am Coffee Break 

11:30 am – 1:00 pm Session II: Immune responses

Chairs: David Durantel & Hélène Strick-Marchand  

•  New advances in the immunobiology of HBV infection –Matteo Iannacone (Milan, Italy) 
• Novel therapeutic vaccines in development – Robert Thimme (Freiburg, Germany) Digital 
• Mechanisms of HBV-HDV interference – Julie Lucifora (Lyon, France) 

Roundtable discussion  

 1:00 pm – 2:00 pm Lunch Break 

2:00 pm – 3:30 pm Session III: Virology 

Chairs: Michael Kann & Patrick Soussan 

•  cccDNA formation and DNA repair processes –Alexander Ploss (Princeton, USA) 
• Crosstalk between HBV and the 3D Genome –Christine Neuveut (Montpellier, France) 
• Targeting HBV cccDNA persistence by gene editing approaches –Barbara Testoni (Lyon, France) 

Roundtable discussion 

3:30 pm – 3:45 pm Tea & Coffee Break

3:45 pm – 5:35 pm Session IV: Assessing the liver reservoir 

Chairs: Massimo Levrero & Vincent Leroy  

•  cccDNA quantification for the investigation of new therapies –Lena Allweiss (Hamburg, Germany) 
• HBV integration and new HBV-associated drivers of hepatocarcinogenesis –Jean-Charles Nault (Paris, France) 
• Assessment of the intrahepatic immune responses  –Adam Gehring (Toronto, Canada) 
• Non invasive biomarkers to monitor the cccDNA reservoir –Sofia Perez del Pulgar (Barcelona, Spain) 

 Roundtable discussion : fine needle aspirates or peripheral biomarkers ?

5.35 pm – 6.00 pm Session V: Roundtable discussion 

Chairs: Harry Janssen & Sofia Perez del Pulgar 

•  What are the remaining key challenges to cure HBV and HDV ? (contributors TBD)

6:00 pm Farewell – Fabien Zoulim

6.00 pm – 7.00 pm Get together cocktail